ABSTRACT
Background- Bronchiectasis is a common chronic respiratory disease. A noticeable drop in lung function during exacerbations and recovery during convalescence has been revealed in patients with asthma or chronic obstructive pulmonary disease (COPD). Hence this study was planned with the objectives to compare lung functions during acute exacerbation and convalescence in patients with bronchiectasis. This was a prospective cohort study Methods- conducted in 50 patients over a duration of 18 months. Measurement of exacerbations and convalescence visits comprised of spirometry, sputum bacteriology, serum and sputum biomarker. Student's paired t test, Fischer's exact test or Chi square test was used to analyze the signicance of difference. P value <0.05 was considered as statistically signicant. In this study, Results- there was a signicant association of mMRC dyspnoea score in exacerbation and in convalescence. (p <0.0001). The analysis showed that mMRC dyspnoea score was shifted to lower scores in convalescence compared to that in exacerbation. FEV1, FVC and FEV1/FVC) and 6 MWT distance were signicantly lower in patients in exacerbation as compared in convalescence. Conclusion- There was marked improvement in lung functions in convalescence as compared to patients in acute exacerbation
ABSTRACT
Objective:To evaluate the clinical curative effect of Huangqi Chifeng Decoction combined with modified Duhuo Jisheng Decoction on patients with ischemic stroke (IS) during recovery.Methods:Prospective cohort study. A total of 220 patients with IS during recovery who met inclusion criteria in the First People's Hospital of Dongcheng District in Beijing, were enrolled and divided into control group ( n=110) and observation group ( n=110) by random number table method between January 2015 and July 2020. The control group was given basic treatment, while observation group was given Huangqi Chifeng Decoction combined with modified Duhuo Jisheng Decoction. All were treated for 1 month. Before and after treatment, Traditional Chinese Medicine (TCM) syndromes were scored. The activities of daily living were evaluated by Barthel index. The quality of life was evaluated by stroke specific quality of life scale (SS-QOL). The severity of neurological impairment was evaluated by National Institute of Health Stroke Scale (NIHSS). The functional recovery of stroke was evaluated by modified Rankin scale (mRS). The adverse reactions during treatment were observed and recorded. Results:After treatment, scores of TCM syndromes, mRS and NIHSS in observation group were significantly lower than those in the control group ( t=21.87, 4.66, 12.06, P<0.01), while scores of Barthel index and SS-QOL were significantly higher than those in the control group ( t=14.13, 5.80, P<0.01). During treatment, there were no obvious adverse reactions in either group. Conclusion:Huangqi Chifeng Decoction combined with modified Duhuo Jisheng Decoction can improve clinical symptoms and nerve function in patients with IS during recovery, which is beneficial to improve outcomes and quality of life.
ABSTRACT
Objective:To study the mechanism of Yangyin Yiqi mixture on the clinical symptoms in convalescent period of different types of pneumonia based on network pharmacology, so as to provide more options for the prevention and treatment of pneumonia with Traditional Chinese Medicine (TCM).Methods:Based on the TCM theory of "treating different diseases with the same method", the Integrative Pharmacology-Based Research Platform of Traditional Chinese Medicine (TCMIP) V 2.0 was used to screen the active components, action targets and disease targets of the herbs in Yangyin Yiqi mixture. The disease-target-medicine network map was constructed by Cytoscape software and the Reactome enrichment analysis of key targets were carried out.Results:Seven different types of clinical sympotms of pneumonia in convalescent period were established, including fatigue, tachypnea, thirst, palpitations, hyperhidrosis, poor appetite and cough. After the screening, a total of 276 active components and 177 key targets were obtained, 37 common targets of this herb and pneumonia were obtained. The key targets were associated with cell metabolism, apoptosis, inflammatory response, immune response, and stress response, etc. There are 17 common targets between Polygonatum and 7 clinical symptoms in the recovery period of different types of pneumonia. Reactome enrichment analysis showed that the pathways involved in the core genes of Yangyin Yiqi mixture in the treatment of the main symptoms of different types of pneumonia in the recovery period were mainly enriched in: by regulating genes and protein translation to affect the virus or cell function, immune regulation and inflammatory response and regulate the function of nervous system, and prevent viral canceration.Conclusions:The effective components in Yangyin Yiqi mixture may regulate phosphatidylinositol 3-kinase (PI3K), interleukin-4, interleukin-13 (IL-4, IL-13) and inhibitory kappa protein (IκBα) by intervention of PIK3CA, MAPK3, BCL2 and NF-κB2 and other targets to promote the recovery of pneumonia. This study could provide a theoretical basis for the prevention and treatment of pneumonia in the recovery period.
ABSTRACT
RESUMEN La convalecencia es la última etapa de la "historia natural de una enfermedad" -si no ocurre la muerte- y con frecuencia no se le presta toda la atención, por lo que no es ocioso revisitar algunos de sus conceptos básicos. Una vez transcurrido un año del inicio de la pandemia inédita del SARS-CoV-2, la mirada se ha vuelto a esta etapa evolutiva de los enfermos y a la identificación y seguimiento de manifestaciones clínicas y posibles secuelas. Con el propósito de profundizar en la importancia de esta etapa en enfermos de COVID-19 y precisar sus características principales, se llevó a cabo este trabajo para contribuir a su mejor comprensión con información actualizada y favorecer los resultados en su manejo. Se abordan los conceptos de alta clínica y alta epidemiológica y la necesidad de valoración del diagnóstico previo. Se insiste sobre los factores que pueden influir en la convalecencia: las características propias de cada persona (biológicas, psicológicas, sociales, culturales y espirituales); el "estado de gravedad" que tuvo el paciente en la fase aguda de la enfermedad y si hubo necesidad de ingreso en cuidados intensivos; los efectos adversos de medicamentos y otros procederes llevados a cabo durante su atención y las comorbilidades.
ABSTRACT Convalescence is the last stage of the "natural history of a disease" - if death does not occur - and it is often not given full attention, so it is not idle to review some of its basic concepts. One year after the onset of the unprecedented SARS-CoV-2 pandemic, the gaze has turned to this evolutionary stage of the patients and to the identification and monitoring of clinical manifestations and possible effect. With the purpose of deepening the importance of this stage in COVID-19 patients and specifying its main characteristics, this work was carried out to contribute to its better understanding with updated information and favor the results in its management. The concepts of clinical discharge and epidemiological discharge and the need to assess the previous diagnosis are addressed. It insists on the factors that can influence convalescence: the characteristics of each person (biological, psychological, social, cultural and spiritual); the "state of seriousness" that the patient had in the acute phase of the disease and whether there was a need for admission to intensive care; adverse effects of medications and other procedures carried out during care and comorbidities.
ABSTRACT
Objective:To investigate Shenqi Fuzheng Injection combined with nimodipine in the treatment of convalescent-phase cerebral infarction and its effects on neurocognitive function, hemorheology and T cell subsets. Methods:A total of 108 patients with cerebral infarction in the convalescent phase who received treatment in Hangzhou Hospital of Traditional Chinese Medicine, China between April 2016 and December 2019 were included in this study. They were randomly assigned to receive either nimodipine treatment (control group, n = 54) or treatment with Shenqi Fuzheng Injection combined with nimodipine (study group, n = 54). Curative effects and changes in neurocognitive function, hemorheology and T cell subsets after treatment relative to before treatment were compared between the control and study groups. Results:Total effective rate in the study group was significantly higher than that in the control group [90.74% (49/54) vs. 75.93% (41/54), χ2 = 4.267, P = 0.039]. After 2 weeks of treatment, whole blood viscosity at a high shear rate, whole blood viscosity at a low shear rate, plasma viscosity in the study group were (4.17 ± 0.24) mPa/s, (9.27 ± 1.98) mPa/s, (1.07 ± 0.19) mPa/s, respectively, which were significantly lower than those in the control group [(4.52 ± 0.31) mPa/s, (13.69 ± 2.13) mPa/s, (1.34 ± 0.23) mPa/s, t = 6.560, 11.169, 6.651, all P < 0.05]. The proportion of CD 3+ cells, CD 4+ and CD 4+/CD 8+ in the study group was (48.59 ± 4.59) %, (44.24 ± 6.17) % and (1.91 ± 0.17) respectively, which were significantly higher than those in the control group [(44.97 ± 5.31) %, (39.55 ± 5.13) %, (1.47 ± 0.22), t = 3.790, 4.295, 11.629, all P < 0.05]. The proportion of CD 8+ cells in the study group was significantly lower than that in the control group [(23.13 ± 5.62) % vs. (26.97 ± 4.26) %, t = 4.001, P < 0.05]. Mini-Mental State Examination score in the study group was significantly higher than that in the control group [(28.87 ± 0.85) points vs. (27.91 ± 1.45) points, t = 4.197, P < 0.05]. National Institute Health of Stroke Scale score in the study group was significantly lower than that in the control group [(9.63 ± 2.19) points vs. (15.27 ± 1.97) points, t = 14.070, P < 0.05]. Conclusion:Shenqi Fuzheng Injection combined with nimodipine can remarkably improve the neurocognitive function, hemorheology and T cell subsets in patients with cerebral infarction in the convalescent phase. The combined method is safe and reliable, and its curative effect is stable.
ABSTRACT
Objective:To evaluate the safety and effectiveness of Tiandan Tongluo capsule in the treatment of cerebral infarction （CI） in convalescence （stoke involving meridians and collaterals due to wind-phlegm-static blood obstructing vessels）， with Naoshuantong capsule as a control. Method:A total of 352 convalescent patients with CI differentiated into stoke involving meridians and collaterals due to wind-phlegm-static blood obstructing vessels in traditional Chinese medicine （TCM） were included in this multi-center， randomized， double-blind， single-simulated， Naoshuantong capsule-controlled clinical trial， which lasted from 28 December， 2016 to 12 April， 2019. After being randomized into an experimental group and a control group at a ratio of 3∶1， patients in the experimental group were provided with oral Tiandan Tongluo capsule， five capsules per time， three times per day， whereas those in the control group received both Naoshuantong capsule simulator， two capsules per time， three times per day， and Naoshuantong capsule， three capsules per time， three times per day， for 12 successive weeks. The patients were followed up until 180 days after onset. The Barthel activities of daily living （ADL） index （BI） score was used as the primary outcome， and the secondary outcomes included neurological deficit score ［assessed with National Institutes of Health Stroke Scale （NIHSS）］， modified Rankin scale （mRS）， TCM syndrome score， and proportion of patients with new vascular events. The changes in laboratory indexes and the incidence of adverse reactions during treatment were observed. Result:Among the 389 cases enrolled， 30 dropped out， with the drop-out rate being 7.71%. There were 374 cases included in the full analysis set and 377 in the safety set. The comparison with the control group revealed that the total BI score and the percentage of BI score ≥ 75 in the experimental group were increased， but the difference was not statistically significant. The percentage of mRS score ≤ 2 within 180 days after onset in the experimental group obviously elevated in contrast to that of the control group （<italic>P</italic><0.05）. As demonstrated by TCM syndrome score analysis， the markedly effective rate in the experimental group was significantly higher than that in the control group （<italic>P</italic><0.05）. During the trial， the incidence rates of new vascular events in the experimental group and the control group were 0.00% and 1.09% （one case）， respectively， exhibiting no statistically significant difference between the two groups. Conclusion:Tiandan Tongluo capsule and Naoshuantong capsule both produce definite therapeutic effects in the treatment of CI in convalescence （stoke involving meridians and collaterals due to wind-phlegm-static blood obstructing vessels）. Compared with Naoshuantong capsule， Tiandan Tongluo capsule better alleviates neurological deficit， promotes neural functional recovery， and improves TCM syndrome score， without inducing severe adverse reactions.
ABSTRACT
Objective:To investigate the effect of Qixian Tongluo prescription on neural function recovery in patients with cerebral infarction and its mechanism. Method:A total of 100 inpatients （January to June，2020）with cerebral infarction in the Neurology Department of Wenzhou Hospital of Traditional Chinese Medicine were assigned to an experimental group （<italic>n</italic>=50） and a control group （<italic>n</italic>=50） according to the random number table. Both groups received conventional treatment of western medicine，while the experimental group took additional Qixian Tongluo prescription. Treatment lasted for 12 weeks. The clinical efficacy，National Institutes of Health Stroke Scale （NIHSS） score， the modified Barthel index （MBI），Fugl-Meyer assessment （FMA） score， and levels of brain-derived neurotrophic factor（BDNF），vascular endothelial growth factor（VEGF）， and stromal cell-derived factor-1（SDF-1） in peripheral blood of the two groups before and after treatment were compared. Result:The total response rate in the experimental group was 84.00%（42/50），higher than 66.00%（33/50） in the control group （<italic>Z</italic>=-7.365，<italic>P</italic><0.05）. There was no significant difference in the scores of MBI，FMA， and NIHSS before treatment between the two groups. The MBI and FMA scores of the two groups increased （<italic>P</italic><0.01）， and the NIHSS scores decreased （<italic>P</italic><0.05， <italic>P</italic><0.01）. Compared with the control group after treatment， the experimental group showed increased MBI and FMA scores and decreased NIHSS score （<italic>P</italic><0.05）. There was no significant difference in BDNF level between the two groups before and after treatment. The VEGF and SDF-1 levels in the peripheral blood of the two groups were higher than those before treatment （<italic>P</italic><0.05）， and the experimental group was higher than the control group （<italic>P</italic><0.05）. Conclusion:Qixian Tongluo prescription can effectively improve the clinical efficacy，the quality of life， and the prognosis of patients with cerebral infarction during convalescence. The underlying mechanism is associated with the promotion of the expression of endogenous VEGF and SDF-1 in the peripheral blood to activate the SDF-1/chemokine receptor 4（CXCR4） signaling pathway， induce the recruitment and mobilization of endothelial progenitor cells， and facilitate the angiogenesis and repair of ischemic brain tissues.
ABSTRACT
Objective:To discuss clinical effect of addition and subtraction therapy of Ditantang combined with Taohong Siwutang to cerebral infarction and syndrome of phlegm and blood stasis blocking collaterals during early recovery， and to study protection to brain nerve. Method:One hundred and fifty-two patients were randomly divided into control group （76 cases） and observation group （76 cases） by random number table， 71 patients in control group completed the therapy （5 patients were falling off， missing visit or eliminated）， and 70 patients in observation group completed the therapy. Both groups' patients got comprehensive rehabilitation measures. Patients in control group got Zhongfeng Huichun pills， 1.5 g/time， 3 times/day. Patients in observation group got addition and subtraction therapy of Ditantang combined with Taohong Siwutang in the morning and at night， 1 dose/day. The treatment was continued for 12 weeks. Before and after treatment， scores of degree of neurological deficit， Barthel （BI） index， Fugl-Meyer scale （FMA）， modified Rankin scale （MRS） and syndrome of phlegm and blood stasis blocking collaterals were graded. And levels of malondialdehyde （MDA）， glutathione peroxidase （GSH-Px）， superoxide dismutase （SOD）， advanced oxidation protein products （AOPP）， vascular endothelial growth factor （VEGF）， brain-derived neurotrophic factor （BDNF） and neuron specific enolase （NSE）. And cerebral hemodynamics were detected， and peak flow velocity （VS）， vascular resistance index （RI）， pulsatility index （PI） and cerebrovascular reserve function （CVR） were recorded. Safety was evaluated. Result:After the 6th week and 12th week of treatment， scores of degree of neurological deficit， BI， FMA， MRS， syndrome of phlegm and blood stasis blocking collaterals， AOPP， MDA， NSE， RI and PI were lower than those in control group （P<0.01）， levels of SOD， GSH-Px， BDNF， VEGF， Vs and CVR were higher than those in control group （P<0.01）. The clinical effect was better than which in control group （Z=2.109， P<0.05）. Besides， there was no adverse reaction caused by Ditantang combined with Taohong Siwutang. Conclusion:Ditantang combined with Taohong Siwutang can ameliarate the hemodynamics， reduce the lipid peroxidation damage， regulate the neurovascular repair factor， so it can promote the repair of nerve tissue and function， clinically reduce the degree of nerve function defect， improve the ability of daily life and exercise when it used to cerebral infarction and syndrome of phlegm and blood stasis blocking collaterals during early recovery， and it is good for clinical effect and safe using.
ABSTRACT
La enfermedad del coronavirus 2019 (COVID-19) causada por la infección por el nuevo coronavirus (SARS-CoV-2) ha creado una pandemia que ha llevado a una lucha mundial para hacer frente al gran número de personas infectadas, muchas de las cuales requieren cuidados intensivos. Hasta la fecha, no existe un tratamiento antivirus específico para COVID-19. El uso de transfusiones de plasma de convalecientes podría ser de gran valor en la pandemia actual. Los pacientes con SRAS-CoV-2 recuperados recientemente que pueden ser donantes adecuados se someten a aféresis para obtener plasma de convalecencia que contenga anticuerpos con títulos elevados, siempre que cumplan los criterios de donación de sangre. En esta revisión, resumimos la literatura existente sobre el plasma convaleciente como una opción terapéutica para COVID-19. Es importante señalar que es necesario estudiar más a fondo el momento adecuado para la administración de plasma de convalecencia y la gravedad de sus efectos adversos. El plasma de convalecencia ofrece la posibilidad de convertirse en una opción de tratamiento prometedora inmediata al evaluar los medicamentos existentes y desarrollar nuevas vacunas y terapias específicas.
The coronavirus disease 2019 (COVID-19) caused by novel coronavirus (SARS-CoV-2) infection has created a pandemic leading to a global struggle to cope with the sheer numbers of infected persons, many of whom require intensive care support. To date, there is no specific antivirus treatment for COVID-19. The use of convalescent plasma transfusions could be of great value in the current pandemic. Recently recovered SARS-CoV-2 patients who may be suitable donors undergo apheresis in order to obtain convalescent plasma containing high-titer antibodies, granted they meet blood donation criteria. In this review, we summarize existing literature around convalescent plasma as a therapeutic option for COVID-19. It is important to note that the appropriate timing on convalescent plasma administration and the severity of its adverse effects needs to be further studied. Convalescent plasma provides the potential to render an immediate promising treatment option while evaluating existing drugs and developing new specific vaccines and therapies.
ABSTRACT
Resumen: La pandemia por COVID-19, originada en diciembre de 2019 en Wuhan, China, obligó a los países, incluido Chile, a un confinamiento masivo para evitar la propagación de SARS-CoV2. Desde marzo de 2020 en Chile, también se afectó la realización de actividad física y deporte en los niños, niñas y adolescentes (NNA). En un esfuerzo por reunir la escasa evidencia disponible sobre el retorno a la práctica de ejercicio en NNA post pandemia COVID-19 y la opinión de expertos de 4 sociedades científicas y académicas (Sociedad Chilena de Medicina del Deporte, Sociedad Chilena de Pediatría, Sociedad Chilena de Kinesiología Deportiva y la Consejo Académico Nacional de Educación Física) se han generado recomendaciones para un retorno seguro a la actividad para el ramo Educación Física y Salud, deporte escolar y federado tanto para disminuir los riesgos asociados a los efectos del confinamiento como para evitar la propagación de COVID-19. Adicionalmente, se incluyen una guía de recomendación para padres y profesores y otra para médicos sobre la vigilancia y evaluación de los pacientes NNA que sostendrán enfermedad COVID-19 y deseen volver al deporte y ejercicio.
Abstract: The COVID-19 pandemic, originated in December 2019 in Wuhan, China, forced a massive quaran tine in most countries including Chile to avoid the propagation of SARS-CoV2. Since March 2020 in Chile, it affected the participation of children and youth athletes as well in education, physical activity and sports. In an effort to assess the scarce available evidence about return to sport and exercise in children and adolescents post COVID-19 pandemic and gather the opinion of experts of 4 Chilean scientific and academic societies (Sociedad Chilena de Medicina del Deporte, Sociedad Chilena de Pediatría, Sociedad Chilena de Kinesiología Deportiva and Consejo Académico Nacional de Edu cación Física) we have produced recommendations for a safe return to activities in Physical Activity and Health class, School Sports and Federation Sports to reduce the risks associated with the effects of confinement and to avoid the propagation of COVID-19 and. Additionally, a recommendation for parents and teachers and a another for physicians for surveillance and evaluation of children and adolescents who were or will become COVID-19 patients and wish to return to sports end exercise.
ABSTRACT
OBJECTIVE: To explore the value of nerve trunk stimulation in the rehabilitation of lower limb function in the patients with cerebral apoplexy at convalescence stage. METHODS: According the random number table, the patients with the lower limb dysfunction of cerebral apoplexy at convalescence stage were divided into a control group and a treatment group, 42 cases in each group. The drug therapy and the routine rehabilitation training were provided in the two groups. Additionally, in the treatment group, the nerve trunk stimulation therapy was adopted， in which, Chize (LU5，stimulating point of radial nerve), Neiguan (PC6, stimulating point of median nerve), Xiaohai (SI8, stimulating point of ulnar nerve) were selected. In the control group, acupuncture intervention was supplemented. Before and after treatment, the peak torque (PT) of the lower flexor-extensor muscle of the knee joint, gait parameters，the score of the modified Ashworth spasm scale (MAS), the score of Fugl-Meyer motor assessment (FMA) and the score of Fugl-Meyer balance scale (FBS) were recorded. RESULTS: After the treatment, the PT of the lower flexor-extensor muscle of the knee joint，the scores of FMA and FBS，the step speed and frequency were all increased, the score of MAS and the difference in the stride between the left and the right were decreased as compared with those before treatment (P<0.01). After the treatment, The PT of the lower flexor-extensor muscle of the knee joint，the scores of FMA and FBS，the step speed and frequency in the treatment group were higher than those in the control group (P<0.01). The score of MAS and the difference in the stride between the left and the right in the treatment group were lower than those in the control group (P<0.01). CONCLUSION: Nerve trunk stimulation therapy quite effectively increases the muscle strength and relieves the muscle tension as well as improves the motor function, the balance and the walking pattern of the lower limbs. This therapy is significantly valuable in the rehabilitation of the lower limbs in the patients with cerebral apoplexy at convalescence stage.
ABSTRACT
Objective:To evaluate peripheral nerve injury in convalescent patients with peripheral paralysis after stroke, and explore the correlation between injured nerve and upper limb motor function. Methods:From December, 2015 to October, 2019, 77 stroke patients were examined motor nerve conduction, F wave, skin sympathetic response (SSR) and electromyography (EMG) on the affected side upper limbs. They were divided into the normal group and the injured group, according to motor nerve conduction. They were assessed with simplified Fugl-Meyer Assessment-Upper Extremities (FMA-UE), and the correlation between the neuroelectrophysiological parameters and FMA-UE score was analyzed. Results:There were 41 patients (53.25%) with peripheral nerve injury (injured group). FMA-UE score was less in the injured group than in the normal group (t = 2.193, P < 0.05), with lower amplitude and occurrence rate of F wave (t > 2.002, P < 0.05), and lower amplitude and shorter latency of SSR (t > 3.140, P < 0.01), although the occurrence rate of F wave and latency of SSR was in the reference range. There was correlation between numbers of injured nerves and FMA-UE score (r = -0.858, P < 0.001). Multivariate linear regression analysis showed that the amplitudes of ulnar, radial and musculocutaneous nerves affected the FMA-UE score (B > 0.317, P < 0.05). Conclusion:There may be peripheral nerves injury for patients with upper limb peripheral paralysis after stroke, which may impair the outcome of motor recovery, and need to be avoided and treated.
ABSTRACT
"\"\\\"[{\\\\\\\"text\\\\\\\": \\\\\\\"Objetivo: identificar as percepções vivenciadas por familiares acompanhantes de crianças durante a\\\\\\\\r\\\\\\\\nhospitalização. Método: pesquisa exploratória, qualitativa, realizada em um setor pediátrico no interior de Mato\\\\\\\\r\\\\\\\\nGrosso, de maio a junho de 2015. Os dados foram obtidos por meio de entrevistas semiestruturadas com os\\\\\\\\r\\\\\\\\nfamiliares de crianças hospitalizadas e submetidos à análise temática. Resultados: as mães estavam mais presentes como acompanhantes durante a hospitalização e que, em alguns casos, aquele foi o primeiro contato com o setor de pediatria. A estrutura física foi considerada satisfatória. Alguns dos sentimentos e atitudes expressados foram desespero, medo, impotência/incapacidade, saudade e esperançaConsiderações finais: o estudo apontou a necessidade de acolhimento dos familiares durante a internação da criança por parte de toda a equipe de saúde, incluindo-os no processo de tratamento, atendendo suas necessidades físicas e psicológicas, contribuindo, desse modo, para a melhoria da assistência à criança.\\\\\\\", \\\\\\\"_i\\\\\\\": \\\\\\\"pt\\\\\\\"}, {\\\\\\\"text\\\\\\\": \\\\\\\"Aim: to identify the perceptions experienced by accompanying relatives of children during hospitalization. Method: exploratory, qualitative research carried out in a pediatric sector in the interior of Mato Grosso from May to June 2015. Data were obtained through semi-structured interviews with the relatives of hospitalized children and submitted to thematic analysis. Results: the mothers were more present as companions during the hospitalization and, in some cases, was the first contact with the pediatrics sector. The physical structure was considered satisfactory. Some of the feelings and expressed attitudes were despair, fear, impotence/ helplessness, longing, and hope. Final considerations: the study pointed out the need of reception of family members by the entire health team during the hospitalization of the child, including them in the treatment process, attending to their physical and psychological needs, thus contributing to the improvement of child care.\\\\\\\", \\\\\\\"_i\\\\\\\": \\\\\\\"en\\\\\\\"}, {\\\\\\\"text\\\\\\\": \\\\\\\"Objetivo: identificar las impresiones vividas por familiares acompañantes de niños durante la hospitalización. Método: investigación exploratoria, cualitativa, realizada en un sector pediátrico en el interior de Mato Grosso, de mayo a junio de 2015. Los datos fueron recolectados por medio de entrevistas semiestructuradas con los familiares de niños hospitalizados y sometidos al análisis temático. Resultados: las madres estaban más presentes como acompañantes durante la hospitalización y, en algunos casos, ese fue el primer contacto con el sector de pediatría. La estructura física fue considerada satisfactoria. Algunos de los sentimientos y actitudes expresados fueron desesperación, miedo, impotencia / incapacidad, nostalgia y esperanza. Consideraciones finales: el estudio destacó la necesidad de la acogida de los familiares durante la internación del niño por parte de todo el equipo de salud, incluyéndolos en el proceso de tratamiento, atendiendo sus necesidades físicas y psicológicas, contribuyendo así para la mejora de la asistencia al niño.\\\\\\\", \\\\\\\"_i\\\\\\\": \\\\\\\"es\\\\\\\"}]\\\"\""
Subject(s)
Humans , Pediatric Nursing , Pediatrics , Family , Child, Hospitalized , ConvalescenceABSTRACT
Background: Ventral hernia is defined as a fascial defectlocated to the abdominal wall. The laparoscopic repair ofIncisional and ventral hernia is fast becoming the standard ofcare.Objectives: To compare and evaluate the post-operative painand convalescence between two groups.Methods: Study was conducted on 30 cases of ventral herniaadmitted in Rajindra Hospital, Patiala. They were divided intotwo comparison groups (15 cases each). Group A: Openventral hernia repair; Group B: Laparoscopic ventral herniarepair.Results and Conclusions: Laparoscopic repair should be thepreferred method of repair of ventral hernia as it is associatedwith a shorter hospital stay, decreased post-operative pain,better cosmetic results decreased complication rate likerecurrence, and seroma formation, decreased mesh infectionrate, early ambulation period, better patient satisfaction andearly return to activities.
ABSTRACT
Objective@#To explore the effect of electrical stimulation breathing training on cardiopulmonary function and quality of life of patients with non-small cell lung cancer during rehabilitation period.@*Methods@#A total of 136 patients with lung cancer who were treated in Harbin Medical University of Cancer Hospital from January 2017 to February 2018 were randomly divided into control group (67 cases) and experimental group (69 cases). Patients in the control group were given routine nursing and treatment, while patients in the experimental group were given electrical stimulation breathing training for 4 weeks on the basis of routine nursing and treatment. Cardiopulmonary function and quality of life were compared between the two groups at 4, 8 and 12 weeks after intervention.@*Results@#The 6-minute walking test results in experimental group for 4, 8 and 12 weeks were (483.36±31.25), (494.61±30.92) and (507.05±32.79) m, which were significantly higher than those in control group (472.06±29.64), (482.85±31.15) and (490.18±32.01) m. The difference was significant (t= 2.162, 2.209, 3.035, all P < 0.01). Borg index in experimental group for 4, 8 and 12 weeks were 1.0 (0.5, 2.0), 0.5 (0.0, 1.0), 0.0 (0.0, 0.5), which were significantly lower than those in control group 2.0 (1.0, 2.0), 1.0 (0.5, 2.0), 0.5 (0.5, 1.0), and 0.5 (0.5, 1.0). The difference was significant (Z= 2.225, 2.692, 3.236, P < 0.05). The scores of physiological function, physiological function, physical pain, general health, vitality, social function, emotional function, mental health of quality of life in experimental group for 12 weeks were (88.42±13.52), (73.64±19.83), (80.51±15.32), (70.22±14.92), (69.64±13.09), (85.28±16.95), (75.93±18.22), (71.24±12.61), which were significantly higher than those in control group (83.14±14.15), (64.51±20.14), (73.15±16.48), (64.68±15.27), (63.96±14.01), (73.59±17.54), (64.07±19.81), (66.35±13.61). The difference was statistically significant (t=2.636-3.636, P < 0.05).@*Conclusions@#Electric stimulation breathing training can improve the cardiopulmonary function and quality of life of patients with non-small cell lung cancer after surgery, and promote lung rehabilitation of patients after surgery, which is worthy of clinical promotion.
ABSTRACT
Objective To explore the effect of electrical stimulation breathing training on cardiopulmonary function and quality of life of patients with non- small cell lung cancer during rehabilitation period. Methods A total of 136 patients with lung cancer who were treated in Harbin Medical University of Cancer Hospital from January 2017 to February 2018 were randomly divided into control group (67 cases) and experimental group (69 cases). Patients in the control group were given routine nursing and treatment, while patients in the experimental group were given electrical stimulation breathing training for 4 weeks on the basis of routine nursing and treatment. Cardiopulmonary function and quality of life were compared between the two groups at 4, 8 and 12 weeks after intervention. Results The 6-minute walking test results in experimental group for 4, 8 and 12 weeks were (483.36 ± 31.25), (494.61 ± 30.92) and (507.05 ± 32.79) m, which were significantly higher than those in control group (472.06±29.64), (482.85±31.15) and (490.18±32.01) m. The difference was significant (t=2.162, 2.209, 3.035, all P<0.01). Borg index in experimental group for 4, 8 and 12 weeks were 1.0 (0.5, 2.0), 0.5 (0.0, 1.0), 0.0 (0.0, 0.5) , which were significantly lower than those in control group 2.0 (1.0, 2.0), 1.0 (0.5, 2.0), 0.5 (0.5, 1.0), and 0.5 (0.5, 1.0). The difference was significant (Z=2.225, 2.692, 3.236, P<0.05). The scores of physiological function, physiological function, physical pain, general health, vitality, social function, emotional function, mental health of quality of life in experimental group for 12 weeks were (88.42 ± 13.52), (73.64 ± 19.83), (80.51 ± 15.32), (70.22 ± 14.92), (69.64 ± 13.09), (85.28 ± 16.95), (75.93 ± 18.22), (71.24±12.61), which were significantly higher than those in control group (83.14±14.15), (64.51± 20.14), (73.15±16.48), (64.68±15.27), (63.96±14.01), (73.59±17.54), (64.07±19.81), (66.35±13.61). The difference was statistically significant (t =2.636-3.636, P < 0.05). Conclusions Electric stimulation breathing training can improve the cardiopulmonary function and quality of life of patients with non-small cell lung cancer after surgery, and promote lung rehabilitation of patients after surgery, which is worthy of clinical promotion.
ABSTRACT
Objective To investigate the effect of acupuncture combined with meridian oxygen therapy on the balance function in convalescent stroke patients.Methods A total of 120 convalescent stroke patients who met the inclusion criteria were divided into 2 groups by random number table method,60 patients in each group.The control group received conventional rehabilitation exercise,and the observation group received acupuncture combined with meridian oxygen therapy on the basis of the control group.Both groups were treated for 4 weeks.The Berg Balance Scale (BBS) was used to evaluate the patients' balance ability,and the therapeutic effect was evaluated according to the change of BBS score before and after treatment.Results The total effective rate was 95.0％ (57/60) in the observation group and 78.3％ (47/60) in the control group,which presented the statistically significant difference between the two groups (x2=13.072,P＜0.01).After 4 weeks treatment,the BBS score of the observation group (46.76 ± 10.82 vs.38.41 ± 10.73,t=-2.575) was significantly higher than that of the control group (P＜0.05).Conclusions acupuncture combined with meridian oxygen therapy can obviously improve the balance and coordination ability of stroke convalescent patients and improve the quality of life of patients.
ABSTRACT
Objective To observe the effect of Yiqi-Yangyin-Quyu decoction combined with acupuncture on serum homocystine level and blood coagulation function of patients with cerebral infarction in convalescent period. Methods A total of 80 patients with cerebral infarction convalescence were divided into the observation group and the control group according to the random number table method, with 40 cases in each group. The control group was given routine treatment of western medicine. Based on this, the observation group was treated with Yiqi-Yangyin-Quyu decoction combined with acupuncture. After 4 weeks of treatment, the Barthel index (BI), neurological impairment National Institutes of Health Stroke Scale (NIHSS), C-reactive protein (CRP), and the level of homocystine (HCY) and blood coagulation function index of plasma prothrombin time (PT), thrombin time (TT), activated partial thromboplastin time (APTT), fibrinogen (FIB)] of the two groups were compared and analyzed. Results The total effective rate of the observation group was 90.0％ (36/40), while the total effective rate of the control group was 70.0％ (28/40). The total effective rate of the 2 groups was statistically significant (Z=-3.184, P=0.004). After treatment, the NIHSS score of the observation group were lower than those of the control group,and the BI score of the observation group were higher than those of the control group(t value were 4.528, 4.337, P<0.05). After treatment, the content of CRP (9.25 ± 1.21 mg/L vs. 15.24 ± 1.74 mg/L, t=4.905) and HCY (12.59 ± 2.05 μmol/L vs. 16.52 ± 2.05 μmol/L, t=4.821) of the observation group were significantly lower than those of the control group (P<0.05). After treatment, the level of PT (15.20 ± 1.17 s vs. 12.95 ± 1.02 s, t=4.891), APTT (36.72 ± 1.98 s vs. 33.02 ± 1.68 s, t=4.553), and TT (14.67 ± 0.95 s vs. 12.21 ± 1.10 s, t=4.210) of the observation group were significantly higher than those of the control group (P<0.05), while the level of FIB (2.55 ± 0.25 g/L vs. 3.03 ± 0.51 g/L, t=4.027) of the observation group was significantly lower than this of the control group (P<0.05). Conclusions The application of Yiqi-Yangyin-Quyu decoction combined with acupuncture can improve the blood coagulation function, reduce the injury of brain tissue, promote the recovery of cerebral nerve function, and improve the quality of life of the patients.
ABSTRACT
Objective To explore effect of Yiqi-Huoxue decoction in combination with exercise rehabilitation therapy on functional recovery of hemiplegic limbs and surface electromyography (Surface electromyography,sEMG) during cerebral infarction convalescence.Methods According to random number table,80 cerebral infarction patients in convalescence stage who met the inclusion criteria were divided into the combination therapy group and rehabilitation therapy group,40 in each group.Rehabilitation therapy group received hemiplegia rehabilitation therapy;combination therapy group took Yiqi-Huoxue decoction on the basis of rehabilitation treatment.The 2 groups were treated for 3 months.In hemiplegic upper limb,Fugl-Meyer Assessment (FMA) was scored and Root Mean Square (RMS) and Median Frequency (MDF) of sEMG on biceps brachii were tested before and after each course of treatment respectively.Results After 1-,2-,or 3-month treatment,FMA score of combination therapy group was significantly higher than that of rehabilitation therapy group (t=2.702,4.595,4.444,respectively;all P＜0.01).At 2 or 3 months after treatment,the RMS of combination therapy group (t=7.188,5.405,respectively;all P＜0.01) and the MDF (t=3.336,4.584,respectively;all P＜0.01) were significantly higher than that of rehabilitation therapy group.Conclusions The Yiqi-Huoxue decoction in combination with exercise rehabilitation therapy can improve motor function and muscle tension of hemiplegic limbs during cerebral infarction convalescence.
ABSTRACT
PURPOSE: This study was a descriptive research to investigate the factors influencing nurses' turnover intention of Senior Convalescence hospitals in the metropolitan area. METHODS: A cross-sectional survey design was used. A questionnaire was distributed to the nurses in Senior Convalescence hospitals. The data of 210 nurses were analyzed using the descriptive statistics, t-test, ANOVA, Pearson correlation coefficient and multiple regression. RESULTS: Turnover intention was significantly correlated with professionalism, job involvement, organizational commitment, job stress, practice environment. Organizational commitment, job stress, age, and practice environment were identified as factors influencing turnover intention. These factors explained 53.3% of variance of turnover intention. CONCLUSION: The results suggest that strategies to decrease turnover intention should be discussed and continued to develop ways to establish organizational commitment, to lower job stress levels and to improve practice environment of nursing work. And further study is needed to identify the key mechanism in nurses' turnover intention of Senior Convalescence hospitals.